Experience
Personal experience is key in providing you with great service. Please take a look below at some of my own projects.
Education
Doctor of Philosophy
Vilcek Institute of Graduate Biomedical Sciences
NYU School of Medicine, New York, NY
Biochemistry and Molecular Biophysics
Master of Science
University of Rhode Island, Kingston, RI
Microbiology
Bachelor of Science
University of Memphis, Memphis, TN
Biology
Publications
Peselis A, Serganov A. Cooperativity and allostery in RNA systems. Methods in Molecular Biology.2021;2253:255-271. https://doi.org/10.1007/978-1-0716-1154-8_15
Shatalin K, Nuthanakanti A, Kaushik A, Shishov D, Peselis A, Shamovsky I, Pani B, Lechpammer M, Vasilyev N, Shatalina E, Rebatchouk D, Mironov A, Fedichev P, Serganov A, Nudler E. Inhibition of bacterial H2S biogenesis targeting antibiotic resistane and tolerance. Science. 2021:372(6547):1169-1175. https://doi.org/10.1126/science.abd8377
Peselis A, Serganov A. ykkC riboswitches employ an add-on helix to adjust specificity for polyanionic ligands. Nature Chemical Biology. 2018;14(9):887-894. https://doi.org/10.1038/s41589-018-0114-4
Peselis A, Gao A, Serganov A. Preparation and crystallization of riboswitches. Methods in Molecular Biology.2016;1320:21-36. https://doi.org/10.1007/978-1-4939-2763-0_3
Ren A, Xue Y, Peselis A, Serganov A, Al-Hashimi HM, Patel DJ. Structural and dynamic basis for low-affinity, high-selectivity binding of L-glutamine by the glutamine riboswitch. Cell Report. 2015;13(9):1800-1813. https://doi.org/10.1016/j.celrep.2015.10.062
Peselis A, Gao A, Serganov A. Cooperativity, allostery and synergism in ligand binding to riboswitches. Biochimie.2015;117:100-109.
Miao Z, Adamiak RW, Blanchet MF, Boniecki M, Bujnicki JM, Chen SJ, Cheng C, Chojnowski G, Chou FC, Cordero P, Cruz JA, Ferré-D’Amaré A, Das R, Ding F, Dokholyan NV, Dunin-Horkawicz S, Kladwang W, Krokhotin A, Lach G, Magnus M, Major F, Mann TH, Masquida B, Matelska D, Meyer M, Peselis A, Popenda M, Purzycka KJ, Serganov A, Stasiewicz J, Szachniuk M, Tandon A, Tian S, Wang J, Xiao Y, Xu X, Zhang J, Zhao P, Zok T, Westhof E. RNA-Puzzles Round II: assessment of RNA structure prediction programs applied to three large RNA structures. RNA. 2015;6:1066-1084. https://doi.org/10.1016/j.biochi.2015.06.028
Peselis A, Serganov A. Themes and variations in riboswitch structure and function. Biochimica and Biophysica Acta. 2014;1839(10):908-918. https://doi.org/10.1016/j.bbagrm.2014.02.012
Peselis A, Serganov A. Structure and function of pseudoknots involved in gene expression control. Wiley Interdisciplinary Review RNA. 2014;5(6):803-822. https://doi.org/10.1002/wrna.1247
Peselis A, Serganov A. Structural insights into ligand binding and gene expression control by an adenosylcobalamin riboswitch. Nature Structural and Molecular Biology. 2012;19(11):1182-1184. https://doi.org/10.1038/nsmb.2405
GRANTS
F31 GM119357-01A1
Mechanism of lnRNA mediated activation of transcription
T32 GM 88118-5
Departmental training grant